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021-54845833/15800441009
中文名稱(chēng)：兔抗AIRE多克隆抗體
英文名稱(chēng)： Anti-AIRE rabbit polyclonal antibody
別 名： APS1; APSI; PGA1; AIRE1; APECED
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃） 避光
宿 主： Rabbit
抗 原： AIRE
反應(yīng)種屬： Human, Mouse, Rat
克隆類(lèi)型： rabbit polyclonal
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Background: |
This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). |
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Applications: |
WB |
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Name of antibody: |
AIRE |
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Immunogen: |
Synthetic peptide of human AIRE |
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Full name: |
autoimmune regulator |
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Synonyms： |
APS1; APSI; PGA1; AIRE1; APECED |
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SwissProt: |
O43918 |
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WB Predicted band size: |
58 kDa |
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WB Positive control: |
MCF7, U937, HT29, OVCAR3 and SW620 cells |
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WB Recommended dilution: |
500-2000 |
