兔抗LEF1多克隆抗體

Background:

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

LEF1

Immunogen:

Fusion protein of human LEF1

Full name:

lymphoid enhancer-binding factor 1

Synonyms：

LEF-1; TCF10; TCF7L3; TCF1ALPHA

SwissProt:

Q9UJU2

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human cervical cancer and Human tonsil

IHC Recommend dilution:

25-100