兔抗GANAB多克隆抗體

Background:

Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.

Applications:

ELISA, IHC

Name of antibody:

GANAB

Immunogen:

Synthetic peptide of human GANAB

Full name:

anaphase promoting complex subunit 11

Synonyms：

APC11; Apc11p; HSPC214

SwissProt:

Q14697

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer and human lung cancer

IHC Recommend dilution:

25-100