兔抗CNTF多克隆抗體

Background:

The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.

Applications:

ELISA, IHC

Name of antibody:

CNTF

Immunogen:

Synthetic peptide of human CNTF

Full name:

ciliary neurotrophic factor

Synonyms:

HCNTF

SwissProt:

P26441

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer and Human gastric cancer

IHC Recommend dilution:

25-50