中文名稱: 兔抗AKAP12多克隆抗體
英文名稱: Anti-AKAP12 rabbit polyclonal antibody
別 名: SSeCKS; AKAP250
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: AKAP12
反應(yīng)種屬: Human
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
AKAP12 |
Immunogen: |
Synthetic peptide of human AKAP12 |
Full name: |
A kinase (PRKA) anchor protein 12 |
Synonyms: |
SSeCKS; AKAP250 |
SwissProt: |
Q02952 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human brain and Human ovarian cancer |
IHC Recommend dilution: |
50-200 |
WB Predicted band size: |
191 kDa |
WB Positive control: |
HT-29 cells |
WB Recommended dilution: |
200-1000 |