ZEB2抗原（重組蛋白）

Full name:

zinc finger E-box binding homeobox 2

Synonyms:

SIP1; SIP-1; ZFHX1B; HSPC082; SMADIP1

Swissprot:

O60315

Gene Accession:

BC127102

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.