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  • PDHB抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW18018
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存：40
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中文名稱：  PDHB抗原（重組蛋白）

英文名稱： PDHB Antigen (Recombinant Protein)

別      名： pyruvate dehydrogenase E1 beta subunit; PDHBD; PHE1B; PDHE1B; PDHE1-B
儲(chǔ)      存： 冷凍（-20℃）
相關(guān)類別： 抗原

概述

Fusion protein corresponding to a region derived from 31-359 amino acids of human PDHB

技術(shù)規(guī)格

Full name:

pyruvate dehydrogenase E1 beta subunit

Synonyms:

PDHBD; PHE1B; PDHE1B; PDHE1-B

Swissprot:

P11177

Gene Accession:

BC000439

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012]