兔抗FAIM2多克隆抗體

Background:

FAIM2 (Fas apoptotic inhibitory molecule 2), also known as LFG (Protein lifeguard), TMBIM2 (Transmembrane BAX inhibitor motif-containing protein 2) and NMP35 (neural membrane protein 35), is a 316 amino acid multipass membrane protein that uniquely protects cells from Fas-induced apoptosis. Though widely expressed, FAIM2 expression is highest in hippocampus. FAIM2 contains seven transmembrane domains and resembles Bax Inhibitor-1, another anti-apoptotic protein. Overexpression of FAIM2 results in decreased caspase activation and reduced incidence of programmed cell death.

Applications:

ELISA, IHC

Name of antibody:

FAIM2

Immunogen:

Fusion protein of human FAIM2

Full name:

Fas apoptotic inhibitory molecule 2

Synonyms：

LFG; LFG2; NGP35; NMP35; TMBIM2

SwissProt:

Q9BWQ8

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human cervical cancer and human tonsil

IHC Recommend dilution:

50-200