兔抗NLRP1多克隆抗體

Background:

This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Applications:

ELISA, IHC

Name of antibody:

NLRP1

Immunogen:

Synthetic peptide of human NLRP1

Full name:

NLR family, pyrin domain containing 1

Synonyms：

NAC; CARD7; CIDED; NALP1; SLEV1; DEFCAP; PP1044; VAMAS1; CLR17.1; DEFCAP-L/S

SwissProt:

Q9C000

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

10-50