兔抗PSMB7多克隆抗體

Background:

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. A pseudogene of this gene is located on the long arm of chromosome 14.

Applications:

ELISA, WB, IHC

Name of antibody:

PSMB7

Immunogen:

Fusion protein of human PSMB7

Full name:

proteasome (prosome, macropain) subunit, beta type, 7

Synonyms：

Z

SwissProt:

Q99436

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and human colon cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

30 kDa

WB Positive control:

Human testis and mouse brain tissue

WB Recommended dilution:

500-2000