兔抗VCL多克隆抗體

Background:

Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

Applications:

ELISA, WB, IHC

Name of antibody:

VCL

Immunogen:

Synthetic peptide of human VCL

Full name:

vinculin

Synonyms：

MVCL, CMD1W, CMH15

SwissProt:

P18206

ELISA Recommended dilution:

5000-240000

IHC positive control:

Human liver cancer and human lung cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

123 kDa

WB Positive control:

Hela cells

WB Recommended dilution:

1000-4000