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  • 兔抗BCAR1(Phospho-Tyr410)多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號 : TW3220
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中文名稱:兔抗BCAR1(Phospho-Tyr410)多克隆抗體

英文名稱: Anti-BCAR1(Phospho-Tyr410) rabbit polyclonal antibody

別      名: CAS; CAS1; CASS1; CRKAS; P130Cas

相關(guān)類別: 一抗

儲      存: 冷凍(-20℃) 避光

宿      主: Rabbit

抗      原: BCAR1(Phospho-Tyr410)

反應(yīng)種屬: Human

標(biāo) 記 物: Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion. Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.

Applications:

WB, IHC

Name of antibody:

BCAR1(Phospho-Tyr410)

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 410(G-V-Y(p)-A-V) derived from Human p130 Cas .

Full name:

breast cancer anti-estrogen resistance 1

Synonyms:

CAS; CAS1; CASS1; CRKAS; P130Cas

SwissProt:

P56945

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

93 kDa

WB Positive control:

K562 cells and NIH/3T3 cells lysates

WB Recommended dilution:

500-1000