兔抗C10orf2多克隆抗體

Background:

This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes.

Applications:

WB, IHC

Name of antibody:

C10orf2

Immunogen:

Fusion protein of human C10orf2

Full name:

chromosome 10 open reading frame 2

Synonyms：

PEO; PEO1; SCA8; ATXN8; IOSCA; PEOA3; SANDO; TWINL; MTDPS7; PRLTS5

SwissProt:

Q96RR1

IHC positive control:

Human liver cancer and Human esophagus cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

77 kDa

WB Positive control:

K562, hela and Jurkat cell

WB Recommended dilution:

500-2000