兔抗CACNA1C多克隆抗體

Background:

This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits.

Applications:

ELISA, IHC

Name of antibody:

CACNA1C

Immunogen:

Synthetic peptide of human CACNA1C

Full name:

calcium channel, voltage-dependent, L type, alpha 1C subunit

Synonyms：

TS; LQT8; CACH2; CACN2; CaV1.2; CCHL1A1; CACNL1A1

SwissProt:

Q13936

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

25-100