兔抗CARMIL1多克隆抗體

Background:

Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments (PubMed:16054028). Plays a role in lamellipodial protrusion formations and cell migration (PubMed:19846667).

Applications:

ELISA, IHC

Name of antibody:

CARMIL1

Immunogen:

Synthetic peptide of human CARMIL1

Full name:

capping protein regulator and myosin 1 linker 1

Synonyms:

CARMIL; LRRC16; LRRC16A; CARMIL1a; dJ501N12.1; dJ501N12.5

SwissProt:

Q5VZK9

IHC positive control:

Human lung cancer

IHC Recommend dilution:

30-150