小鼠抗LGALS3單克隆抗體

Background:

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010].

Applications:

WB, IHC, IF

Name of antibody:

LGALS3

Immunogen:

Fusion protein of human LGALS3

Full name:

lectin, galactoside-binding, soluble, 3 (LGALS3), transcript variant 1

Synonyms:

CBP35; GAL3; GALBP; GALIG; L31; LGALS2; MAC2

SwissProt:

P17931

IHC positive control:

human pancreas tissue and carcinoma of human pancreas tissue; human kidney tissue and carcinoma of human kidney tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

26 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, MDCK, PC12, MCF-7 cell lysates

WB Recommended dilution:

500-2000