兔抗HDAC6(Phospho-Ser22) 多克隆抗體

Background:

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

Applications:

WB

Name of antibody:

HDAC6(Phospho-Ser22)

Immunogen:

Peptide sequence around phosphorylation site of serine 22 (P-Q-S(p)-P-P) derived from Human HDAC6.

Full name:

histone deacetylase 6

Synonyms：

HD6; JM21; CPBHM; PPP1R90

SwissProt:

Q9UBN7

WB Predicted band size:

131 kDa

WB Positive control:

NIH/3T3 cells lysates

WB Recommended dilution:

500-1000