兔抗HOXA1多克隆抗體

Background:

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. Two transcript variants encoding two different isoforms have been found for this gene, with only one of the isoforms containing the homeodomain region.

Applications:

ELISA, IHC

Name of antibody:

HOXA1

Immunogen:

Synthetic peptide corresponding to a region derived from 17-33 amino acids of human HOXA1

Full name:

homeobox A1

Synonyms:

BSAS; HOX1; HOX1F

SwissProt:

P49639

ELISA Recommended dilution:

5000-10000

IHC Positive control:

Human esophagus cancer;

IHC Recommended dilution:

20-100