兔抗HSD3B7多克隆抗體

Background:

This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

HSD3B7

Immunogen:

Fusion protein of human HSD3B7

Full name:

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7

Synonyms：

CBAS1; PFIC4; SDR11E3

SwissProt:

Q9H2F3

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human prostate cancer and human brain

IHC Recommend dilution:

50-200