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021-54845833/15800441009
英文名稱：ABCB8 Antigen (Recombinant Protein)
儲 存：冷凍（-20℃）
概述
Fusion protein corresponding to a region derived from 394-693 amino acids of human ABCB8
技術(shù)規(guī)格
Full name:
ATP-binding cassette sub-family B member 8
Synonyms:
MABC1, M-ABC1, EST328128
Swissprot:
Q9NUT2
Gene Accession:
BC141836
Purity:
>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:
Escherichia coli
Tags:
His tag C-Terminus, GST tag N-Terminus
Background:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.
