兔抗MVK多克隆抗體

Background:

This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash.

Applications:

ELISA, WB, IHC

Name of antibody:

MVK

Immunogen:

Fusion protein of human MVK

Full name:

mevalonate kinase

Synonyms：

MK; LRBP; MVLK; POROK3

SwissProt:

Q03426

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer and Human esophagus cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

42 kDa

WB Positive control:

Raji cells

WB Recommended dilution:

200-1000