兔抗PPHLN1多克隆抗體

Background:

The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Applications:

WB, IHC

Name of antibody:

PPHLN1

Immunogen:

Synthesized peptide derived from internal of human PPHLN.

Full name:

periphilin 1

Synonyms：

HSPC206; HSPC232

SwissProt:

Q8NEY8

IHC positive control:

Human liver carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

53 kDa

WB Positive control:

COLO cells and 293 cells lysates

WB Recommended dilution:

500-3000