兔抗SOCS3多克隆抗體

Background:

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.

Applications:

ELISA, WB, IHC

Name of antibody:

SOCS3

Immunogen:

Fusion protein of human SOCS3

Full name:

suppressor of cytokine signaling 3

Synonyms：

CIS3, SSI3, ATOD4, Cish3, SSI-3, SOCS-3

SwissProt:

O14543

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human liver cancer and human lung cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

25 kDa

WB Positive control:

Mouse heart tissue

WB Recommended dilution:

500-2000