兔抗SOCS2多克隆抗體

Background:

This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor.

Applications:

ELISA, IHC

Name of antibody:

SOCS2

Immunogen:

Fusion protein of human SOCS2

Full name:

suppressor of cytokine signaling 2

Synonyms：

CIS2; SSI2; Cish2; SSI-2; SOCS-2; STATI2

SwissProt:

O14508

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human brain

IHC Recommend dilution:

25-100