兔抗TIA1多克隆抗體

Background:

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.

Applications:

ELISA, WB, IHC

Name of antibody:

TIA1

Immunogen:

Full length fusion protein

Full name:

TIA1 cytotoxic granule-associated RNA binding protein

Synonyms:

WDM; TIA-1

SwissProt:

P31483

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer and human tonsil

IHC Recommend dilution:

40-250

WB Predicted band size:

43 kDa

WB Positive control:

HEPG2 and NIH/3T3 cell lysates

WB Recommended dilution:

1000-5000