相關類別: 一抗
Background: |
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
IL2RB |
Immunogen: |
Fusion protein of human IL2RB |
Full name: |
interleukin 2 receptor, beta |
Synonyms: |
CD122; IL15RB; P70-75 |
SwissProt: |
P14784 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human thyroid cancer and human cervical cancer |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
61 kDa |
WB Positive control: |
231, 293T, Raji and hela cells |
WB Recommended dilution: |
500-2000 |