兔抗CBR1多克隆抗體

Background:

Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol.

Applications:

ELISA, WB, IHC

Name of antibody:

CBR1

Immunogen:

Fusion protein of human CBR1

Full name:

carbonyl reductase 1

Synonyms：

CBR; hCBR1; SDR21C1

SwissProt:

P16152

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human breast cancer and human esophagus cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

30 kDa

WB Positive control:

Mouse liver and human fetal lung tissue, hela cells and mouse kidney tissue, human brain malignant glioma tissue

WB Recommended dilution:

1000-5000