兔抗CD247多克隆抗體

Background:

The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

CD247

Immunogen:

Fusion protein of human CD247

Full name:

CD247 molecule

Synonyms:

T3Z; CD3H; CD3Q; CD3Z; TCRZ; IMD25; CD3-ZETA

SwissProt:

P20963

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer and human thyroid cancer

IHC Recommend dilution:

25-100