技術規(guī)格
Background: |
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit |
Applications: |
IHC |
Name of antibody: |
IRS1(Phospho-Ser307) |
Immunogen: |
Peptide sequence around phosphorylation site of serine 307(T-E-S(p)-I-T) derived from Human IRS-1. |
Full name: |
insulin receptor substrate 1 |
Synonyms: |
HIRS-1 |
SwissProt: |
P35568 |
IHC positive control: |
Human breast carcinoma tissue |
IHC Recommend dilution: |
50-100 |