兔抗CFTR多克隆抗體

Background:

This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene.

Applications:

ELISA, IHC

Name of antibody:

CFTR

Immunogen:

Synthetic peptide of human CFTR

Full name:

Cystic fibrosis transmembrane conductance regulator

Synonyms：

CF, MRP7, ABC35, ABCC7, CFTR/MRP, TNR-CFTR, dJ760C5.1

SwissProt:

P13569

ELISA Recommended dilution:

500-5000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

10-50