小鼠抗ACADM單克隆抗體

Background:

This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Applications:

WB, IHC

Name of antibody:

ACADM

Immunogen:

Fusion protein of human ACADM

Full name:

acyl-CoA dehydrogenase medium chain

Synonyms:

MCAD; ACAD1; MCADH

SwissProt:

P11310

IHC positive control:

Human colon tissue and Human spleen tissue; Human breast cancer and Human liver tissue

IHC Recommend dilution:

200-500

WB Predicted band size:

47 KD

WB Positive control:

Hela, HepG2 cell lysates

WB Recommended dilution:

500-2000