兔抗AADACL2多克隆抗體

Background:

AADAC is a 45 kDa membrane-associated hydrolase highly expressed in the human liver that has been implicated in the hydrolysis of arylacetamide xenobiotics including flutamide and phenacetin.556–560AADAC is highly homologous to several related lipases, AADACL1, 2, and 4, the latter two of which remain completely unannotated. Overexpression of AADAC in a rat hepatoma cell line produces changes in cellular TG levels, apoplipoprotein B secretion, and fatty acid oxidation, but the mechanism for these effects remains unclear.561 Candidate endogenous substrates, selective inhibitors, or knockout mice have not, to our knowledge, been described for AADAC or the related enzymes AADACL2 and AADACL4.

Applications:

ELISA, IHC

Name of antibody:

AADACL2

Immunogen:

Fusion protein of human AADACL2

Full name:

arylacetamide deacetylase-like 2

SwissProt:

Q6P093

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human cervical cancer and human thyroid cancer

IHC Recommend dilution:

25-100