兔抗ATP2A1多克隆抗體

Background:

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.

Applications:

ELISA, IHC

Name of antibody:

ATP2A1

Immunogen:

Synthetic peptide of human ATP2A1

Full name:

ATPase, Ca++ transporting, cardiac muscle, fast twitch 1

Synonyms：

ATP2A; SERCA1

SwissProt:

O14983

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and Human brain

IHC Recommend dilution:

50-200