中文名稱:CLEC7A抗原(重組蛋白)
英文名稱:CLEC7A Antigen (Recombinant Protein)
儲(chǔ) 存:冷凍(-20℃)
相關(guān)類別:抗原
概述
Fusion protein corresponding to a region derived from 1-77 amino acids of human CLEC7A |
技術(shù)規(guī)格
Full name: |
C-type lectin domain containing 7A |
Synonyms: |
BGR; CD369; CANDF4; SCARE2; DECTIN1; CLECSF12 |
Swissprot: |
Q9BXN2 |
Gene Accession: |
BC013385 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. |