中文名稱:COX7B2抗原(重組蛋白)
英文名稱:COX7B2 Antigen (Recombinant Protein)
儲 存:冷凍(-20℃)
相關(guān)類別:抗原
概述
Fusion protein corresponding to a region derived from 2-81 amino acids of human COX7B2 |
技術(shù)規(guī)格
Full name: |
cytochrome c oxidase subunit VIIb2 |
Swissprot: |
Q8TF08 |
Gene Accession: |
BC035923 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water and ATP. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. COX7b (cytochrome c oxidase subunit VIIb polypeptide) and COX7b2 (cytochrome c oxidase subunit VIIb polypeptide 2) are 80 and 81 amino acid proteins, respectively, which exist as components of the COX complex, therefore playing an important role in electron transport. A rare polymorphism in the COX7b2 gene at codon 26 may be linked to nasopharyngeal carcinoma (NPC), the most common head and neck cancer in southern China. |