中文名稱:CPT1A抗原(重組蛋白)
英文名稱:CPT1A Antigen (Recombinant Protein)
儲 存:冷凍(-20℃)
相關(guān)類別:抗原
概述
Fusion protein corresponding to C terminal 300 amino acids of human CPT1A |
技術(shù)規(guī)格
Full name: |
carnitine palmitoyltransferase 1A (liver) |
Synonyms: |
CPT1, CPT1-L, L-CPT1 |
Swissprot: |
P50416 |
Gene Accession: |
BC000185 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |