小鼠抗SERPINB4單克隆抗體

Background:

The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme that kills tumor cells. This protein, along with serpin B3, can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation.

Applications:

ELISA, WB

Name of antibody:

SERPINB4

Immunogen:

Fusion protein of human SERPINB4

Full name:

serpin family B member 4

Synonyms:

PI11; SCCA1; SCCA2; LEUPIN; SCCA-2

SwissProt:

P48594

WB Predicted band size:

45 kDa

WB Positive control:

Jurkat whole cell lysate

WB Recommended dilution:

500-2000