兔抗ABCD4多克隆抗體

Background:

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding.

Applications:

ELISA, WB

Name of antibody:

ABCD4

Immunogen:

Synthetic peptide of human ABCD4

Full name:

ATP-binding cassette, sub-family D (ALD), member 4

Synonyms：

P70R; P79R; ABC41; MAHCJ; PMP69; PXMP1L; EST352188

SwissProt:

O14678

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

69 kDa

WB Positive control:

Jurkat cells

WB Recommended dilution:

200-1000