Background: |
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. |
Applications: |
WB |
Name of antibody: |
CHUK(Phospho-Ser180/181) |
Immunogen: |
Peptide sequence around phosphorylation site of serine 180/181 (C-T-S(p)-F-V) derived from Human IKK- alpha/ beta. |
Full name: |
conserved helix-loop-helix ubiquitous kinase |
Synonyms: |
IKK1; IKKA; IKBKA; TCF16; NFKBIKA; IKK-alpha |
SwissProt: |
O15111 |
WB Predicted band size: |
85 kDa |
WB Positive control: |
HepG2 cells lysates treated with TNF |
WB Recommended dilution: |
500-1000 |