兔抗CHURC1多克隆抗體

Background:

CHURC1, also known as protein Churchill, is a 112 amino acid protein that plays a critical role in neural induction during embryogenesis. The fibroblast growth family of proteins (FGFs) has been identified as necessary factors in mesoderm formation and neural induction. CHURC1, a putative zinc finger protein, is a transcriptional activator that mediates FGF signaling. Furthermore, CHURC1 is thought to play a role in the regulation of cell movement. Although CHURC1 does not bind to DNA, it functions as a transcriptional regulator and a protein-interaction factor. Two isoforms of CHURC1 exist as a result of alternative splicing events.

Applications:

ELISA, IHC

Name of antibody:

CHURC1

Immunogen:

Synthetic peptide of human CHURC1

Full name:

churchill domain containing 1

Synonyms:

chch; My015; C14orf52

SwissProt:

Q8WUH1

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer

IHC Recommend dilution:

20-100