兔抗CLDN19多克隆抗體

Background:

he product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Applications:

WB

Name of antibody:

CLDN19

Immunogen:

Synthesized peptide derived from internal of human CLDN19.

Full name:

claudin 19

Synonyms：

HOMG5

SwissProt:

Q8N6F1

WB Predicted band size:

23 kDa

WB Positive control:

HepG2 cells and Jurkat cells lysates

WB Recommended dilution:

500-3000