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    • 品牌 : 通蔚生物
    • 目錄號 : TW15310
    • 應用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱:  兔抗COL25A1多克隆抗體 

英文名稱: Anti-COL25A1 rabbit polyclonal antibody

別      名: collagen type XXV alpha 1; AMY; CLAC; CLACP; CFEOM5; CLAC-P

相關(guān)類別: 一抗

抗      原: COL25A1

儲      存: 冷凍(-20℃)

宿      主: Rabbit

反應種屬: Human, Mouse

標  記 物: Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

COL25A1

Immunogen:

Synthetic peptide of human COL25A1

Full name:

collagen type XXV alpha 1

Synonyms:

AMY; CLAC; CLACP; CFEOM5; CLAC-P

SwissProt:

Q9BXS0

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

65 kDa

WB Positive control:

A549,Jurkat and A172 cell,Human testis tissue,Hela cell lysates

WB Recommended dilution:

200-1000