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  • ABCB7抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號 : TW16101
    • 應用 : 僅限于科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱： ABCB7 抗原（重組蛋白）
英文名稱： ABCB7 Antigen (Recombinant Protein)
別       名： ATP-binding cassette, sub-family B (MDR/TAP), member 7; ABC7; ASAT; Atm1p; EST140535
儲       存： 冷凍（-20℃）
相關類別： 抗原

概述
Fusion protein corresponding to a region derived from 501-753 amino acids of human ABCB7

技術規(guī)格

Full name:

ATP-binding cassette, sub-family B (MDR/TAP), member 7

Synonyms:

ABC7; ASAT; Atm1p; EST140535

Swissprot:

O75027

Gene Accession:

BC006323

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.