兔抗CTAG1A/B多克隆抗體

Background:

The protein encoded by this gene is an antigen that is overexpressed in many cancers but that is also expressed in normal testis. This gene is found in a duplicated region of the X-chromosome and therefore has a neighboring gene of identical sequence. Expressed in testis and ovary and in a wide variety of cancers. Detected in uterine myometrium. Expressed from 18 weeks until birth in human fetal testis. In the adult testis, is strongly expressed in spermatogonia and in primary spermatocytes, but not in post-meiotic cells or in testicular somatic cells (at protein level).

Applications:

ELISA, IHC

Name of antibody:

CTAG1A/B

Immunogen:

Synthetic peptide of human CTAG1A/B

Full name:

Cancer/testis antigen 1

Synonyms:

CTAG, CTAG1, ESO1, LAGE2, LAGE2A/CTAG1B

SwissProt:

P78358/P78358

IHC positive control:

Human gastric cancer and human thyroid cancer

IHC Recommend dilution:

25-100