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  • CEP290 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16201
    • 應(yīng)用 : 僅限于科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:60
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中文名稱(chēng): CEP290 抗原(重組蛋白)

英文名稱(chēng): CEP290 Antigen (Recombinant Protein)

別     名: centrosomal protein 290; CT87; MKS4; POC3; rd16; BBS14; JBTS5; LCA10; NPHP6; SLSN6; 3H11Ag

儲(chǔ)     存: 冷凍(-20℃)

相關(guān)類(lèi)別: 抗原

概     述

Fusion protein corresponding to a region derived from 941-1104 amino acids of human CEP290

技術(shù)規(guī)格

Full name:

centrosomal protein 290

Synonyms:

CT87; MKS4; POC3; rd16; BBS14; JBTS5; LCA10; NPHP6; SLSN6; 3H11Ag

Swissprot:

O15078

Gene Accession:

BC008641

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.