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  • BCL7A抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16288
    • 應(yīng)用 : 僅限于科研使用
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中文名稱: BCL7A抗原(重組蛋白)

英文名稱: BCL7A Antigen (Recombinant Protein)

別       名: B-cell CLL/lymphoma 7A; BCL7

相關(guān)類別: 抗原

儲(chǔ)       存: 冷凍(-20℃)

概述

Fusion protein corresponding to N terminal 187 amino acids of human BCL7A

技術(shù)規(guī)格

Full name:

B-cell CLL/lymphoma 7A

Synonyms:

BCL7

Swissprot:

Q4VC05

Gene Accession:

BC113627

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.