兔抗AKT2多克隆抗體

Background:

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

Applications:

ELISA, IHC

Name of antibody:

AKT2

Immunogen:

Synthetic peptide of human AKT2

Full name:

v-akt murine thymoma viral oncogene homolog 2

Synonyms：

PKBB; PRKBB; HIHGHH; PKBBETA; RAC-BETA

SwissProt:

P31751

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human brain and Human breast cancer

IHC Recommend dilution:

50-200