兔抗DACT1多克隆抗體

Background:

The protein encoded by this gene belongs to the dapper family, characterized by the presence of PDZ-binding motif at the C-terminus. It interacts with, and positively regulates dishevelled-mediated signaling pathways during development. Depletion of this mRNA from xenopus embryos resulted in loss of notochord and head structures, and mice lacking this gene died shortly after birth from severe posterior malformations. Alternatively spliced transcript variants have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

DACT1

Immunogen:

Synthetic peptide of human DACT1

Full name:

dishevelled binding antagonist of beta catenin 1

Synonyms:

DPR1; FRODO; HDPR1; DAPPER; THYEX3; DAPPER1

SwissProt:

Q9NYF0

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer and Human tonsil

IHC Recommend dilution:

20-100