中文名稱:兔抗RNF126多克隆抗體
英文名稱: Anti-RNF126 rabbit polyclonal antibody
相關(guān)類別: 一抗
儲(chǔ) 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: RNF126
反應(yīng)種屬: Human, Mouse, Rat
標(biāo)記物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. RNF126 interacts with p21 and RNF126 over-expression increased p21 protein ubiquitination in an E3 ligase activity-dependent manner. RNF126 knockdown induced loss of cell viability in MDA-MB-231 and PC-3 can be partially rescued by depletion of p21. RNF126 stable knockdown in PC3 inhibited tumor growth in SCID mice. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
RNF126 |
Immunogen: |
Synthetic peptide of human RNF126 |
Full name: |
Ring finger protein 126 |
SwissProt: |
Q9BV68 |
ELISA Recommended dilution: |
1000-5000 |
IHC positive control: |
Human thyroid cancer and Human brain |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
38 kDa |
WB Positive control: |
Jurkat and K562 cells |
WB Recommended dilution: |
500-2000 |