兔抗DACH2多克隆抗體

Background:

This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

DACH2

Immunogen:

Fusion protein of human DACH2

Full name:

dachshund family transcription factor 2

SwissProt:

Q96NX9

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and Human liver cancer

IHC Recommend dilution:

50-200